Journal of Oral Medicine, Oral Surgery, Oral Pathology and Oral Radiology


Efficacy of transdermal diclofenac patches in the treatment of pain associated with various temporomandibular joint disorders: A comparative study


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Article Type : Research Article

Author Details: Altaf Hussain,Rayees Ahmad,Nusrat Nazir*

Volume : 5

Issue : 2

Online ISSN : 2395-6194

Print ISSN : 2395-6186

Article First Page : 37

Article End Page : 41


Abstract

Introduction: Temporomandibular disorders (TMD) is a term used to describe collectively a number of related disorders affecting the temporomandibular joints, masticatory muscles, and associated structures. The treatment modalities include surgical and non-surgical methods. In this study non-surgical method was used. The aim of present study was to evaluate and compare the efficacy of topical and systemic NSAIDs in the management of pain of TMD origin.
Materials and Methods: A single blinded cross-sectional study was conducted and a total of 40 clinically diagnosed cases of TMDs of muscular origin were selected. Once the diagnosis of myalgia due to TMD was made, the patients were randomly allocated in one of the treatment groups. The study divided the participants into 2 categories: GROUP A: oral diclofenac 50mg, and Thiocholchicocide 4mg 12 hourly for 15 days. GROUP B: 200mg of transdermal patch of diclofenac to be applied over the masseter muscle 12 hourly and Thiocolchicoside 4mg twice daily as in group A for the period of 15 days.
Results: Females where most commonly affected with a ratio of 2.07:1 and a mean age of 33.5 years. For group A mean verbal rating score of pain was 8, 5, 4, 1 on 3rd, 7th, 15th, and 21ist day respectively and group B mean verbal rating score of pain was 7, 5, 3, 1 on 3rd, 7th, 15th, and 21ist day respectively. There was no significant difference in trends of pain intensity in patients treated by oral NSAIDS and patients who were treated with Transdermal patch group.
Conclusion: There was no significant difference in trends of pain intensity in patients treated by oral NSAIDS and patients who were treated with Transdermal patch group. However treatment with topical NSAIDs has been shown to provide clinically effective analgesia at the site of application while minimizing systemic absorption.

Keywords: Transdermal diclofenac patch, Thiocholchicoside, Gamma amino butyric acid, Temporomandibular joint disorders.

Doi :-https://doi.org/10.18231/j.jooo.2019.011