Indian Journal of Pharmacy and Pharmacology


Phytochemical analysis and Antimicrobial activity of HAGENIA ABYSSINICA


Full Text PDF



Author Details: Tesfaye Wolde, Behailu Bizuayehu, Tesfaye Hailemariam, Kassahun Tiruha

Volume : 3

Issue : 3

Online ISSN : 2393-9087

Print ISSN : 2393-9079

Article First Page : 127

Article End Page : 134


Abstract

Introduction: Ethiopian communities highly depend on local plants to safe and sound their survival and health. Local trees are subjugated and used intensively for medicinal uses.
Objective: The aim of the present study was too carried out phytochemical analysis of organic extract of Hagenia abyssinica and to find out antihelmentic property of Hagenia abyssinica.
Methods: Hagenia abyssinica female flower extracts was used for plant component analysis and for determination of antihelmentic activity. Earth worm (Pheretima posthuma) strains were used for experimental purpose. Disc diffusion method was used to assess the antibacterial effect of the extracts on micro-organisms.
Results: The phytochemical screening indicated the presence of flavonoids, tannins, steroid, alkaloid, saponins in all extracts. Antibacterial and antihelmentic activity of Ethanolic, Methanolic, Hexane and Petroleum Ether extract of Hagenia abyssinica female flowers was highly active against Adult earthworm (Pheritima posthuma) and active against Staphyloccoccus aureus and showed less activity against Salmonella typhi.
Conclusion: The present study finally demonstrates that Hagenia abyssinica is a good source of various phytochemical such as Saponins, Phlobathanins, Flavonoids, Anthraquinones, Phenols, Terpenoids, Alkaloids, Steroids, Glycosides, Tannins. The antibacterial activity Hagenia abyssinica was clearly shown by the present study against bacteria. All these preliminary reports affirm an in depth analysis of the usefulness of Hagenia abyssinica as miracle drug against various ailments.

Keywords:
Antimicrobial activity; Hagenia abyssinica ; Phytochemicals; Traditional medicine

Doi No:-10.18231