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IP Journal of Urology, Nephrology & Hepatology Science


The relation of liver enzymes and laparoscopic appendectomy


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Author Details: Kalpana Ashfaque,Mohammed Ashfaque*,Elroy Saldanha,Reshmina Clara D'Souza

Volume : 1

Issue : 2

Online ISSN : XXXX

Print ISSN : XXXX

Article First Page : 16

Article End Page : 17


Abstract

Introduction: Acute appendicitis is one of the most common surgical emergencies with a lifetime prevalence of approximately 1 in 7.1 Appendectomy remains the only curative treatment of appendicitis which is the common surgical emergency, hence appendectomy is one of the most common surgeries performed by a general surgeon. Laparoscopy is a minimally invasive access to the peritoneal cavity for both diagnosis and many surgical interventions which were previously possible only by open surgeries. Laparoscopic surgeries have an advantage that there is a reduction in patient morbidity, reduction in the duration of hospitalization and early return to normal activity. It has been noticed that, following laparoscopic surgery, the level of certain serum liver enzymes rose markedly in most patients who had shown normal LFT. This observation raised several questions this study to assessed the prevalence of disturbances in liver enzymes following laparoscopic appendectomies. The study was a prospective experimental study conducted on 100 cases evaluated and diagnosed as acute appendicitis and were admitted to Hospital who underwent laparoscopic appendectomy from the time period. The study was done at the KMC medical college at Mangalore, AJ medical college Mangalore, and at the unity hospital Mangalore.
The levels of serum bilirubin, serum alanineamino transferase (ALT), serum aspartate aminotransferase (AST) and serum alkaline phosphatase were all measured pre-operatively once and then post-operatively on Day 1 and Day 7.
Results: In our post operatively statistically significantly with a p value <0>post operatively study we found that the alkaline phosphatase levels, conjugated bilirubin, uncongugated bilirubin  levels, SGOT levels, SGPT levels increased first day

Doi No:-10.18231