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Journal of Oral Medicine, Oral Surgery, Oral Pathology and Oral Radiology


Basement membrane in health and disease- an enigma to histopathologist


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Author Details: Vijaykumar Biradar, Namita Shrivastav, Priya Shree, Rakhee Sinha, Akhilanand Chaurasia

Volume : 4

Issue : 2

Online ISSN : 2395-6194

Print ISSN : 2395-6186

Article First Page : 100

Article End Page : 105


Abstract

 

 

Basement membrane is known to play a role in the pathogenesis of inflammatory, tumor invasion, metastases and autoimmune diseases. A basement membrane (BM) is a thick sheet of extracellular matrix molecules, upon which epithelial cells attach and form a boundary between epithelium and the connective tissue. It also provides structural support for epithelial, mesothelial, and endothelial cells and surrounds adipocytes, muscles and Schwann cells. This literature review describes terminologies, histology, ultrastructure, molecular aspects, functions and histochemical studies of basement membrane in health and disease.

Keywords: Basement membrane, Extracellular matrix, Health, Disease

 

 

Doi No:-10.18231/2395-6194.2018.0024