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IP Archives of Cytology and Histopathology Research

Comparative evaluation of gastric biopsies for detection of Helicobacter pylori

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Author Details : Dhruv Mehra*

Volume : 4, Issue : 4, Year : 2019

Article Page : 361-362

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Helicobacter pylori earlier known as Campylobacter pylori is a gram negative bacterias that colonizes the
gastric epithelium of Humans.
Helicobacter pylori is considered as the most successful pathogen as more than 50% population have
Helicobacter pylori in their upper Gastrointestinal tract.
It is usually observed that 80% of the infected population is asymptomatic to the bacterium. The infection of
Helicobacter pylori is more common in developing countries like India than developed western countries.
Helicobacter pylori is a major cause of gastro-duodenal injury and is also related to gastric cancer, thus
detection of the bacterium is must for proper treatment.
This paper is a comparative evaluation of traditional stains used for the diagnosis of H. pylori. Main focus
is laid on special stains such as Giemsa stain, toluidine blue and modified H&E staining method.
The most common way of detecting Helicobacter pylori is by histopathological examination in which
biopsies from stomach region (Body, fundus and antrum) are examined.

Keywords: Helicobacter pylori diagnosis histopathology, GI Biopsies tissue staining.

Doi : 10.18231/j.achr.2019.071

How to cite : Mehra D, Comparative evaluation of gastric biopsies for detection of Helicobacter pylori. IP Arch Cytol Histopathol Res 2019;4(4):361-362

Copyright © 2019 by author(s) and IP Arch Cytol Histopathol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (