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IP Archives of Cytology and Histopathology Research


A case report on oesophageal schwannoma: A rare occurrence


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Author Details : Iffat Jamal

Volume : 1, Issue : 1, Year : 2016

Article Page : 36-38


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Abstract

Most tumorous lesions of the esophagus are esophageal cancers. Benign primary tumors of the esophagus are uncommon, and account for approximately 2% of all esophageal tumors. More than 80% of benign esophageal tumors are leiomyomas, with schwannomas being rare. A 55-year-old man visited our internal medicine department with complaints of palpitations and discomfort during swallowing. A chest computed tomography scan showed a lobulated tumor (5x4x2 cm) in the upper to middle mediastinum, with homogenous inner opacity, compressing the esophagus. Upper gastrointestinal endoscopy revealed a smooth-surfaced elevated lesion covered with normal mucosa, and a schwannoma was diagnosed based on the biopsy result. Histopathological examination revealed spindle-shaped cells in a fasciculated and disarrayed architecture and nuclei in a palisading pattern. Immunohistochemical studies revealed S100 protein positivity and the absence of staining for α smooth muscle actin (αSMA), CD34 and CD117, thereby establishing the diagnosis of benign schwannoma. Her postoperative course was uneventful and there has been no evidence of recurrence to date.

Keywords:
Schwannoma, Leiomyoma, Mediastinum, Palisading, Submucosa

How to cite : Jamal I, A case report on oesophageal schwannoma: A rare occurrence. IP Arch Cytol Histopathol Res 2016;1(1):36-38

Copyright © 2016 by author(s) and IP Arch Cytol Histopathol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)