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IP Archives of Cytology and Histopathology Research

Multicystic dysplastic kidney: Ten-year evaluation

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Research Article

Author Details : B U Sowmya, V S Nandish*, Prema Saldanha

Volume : 4, Issue : 3, Year : 2019

Article Page : 216-219

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Introduction: Multicystic dysplastic kidney (MCDK) is the most common form of developmental
abnormality seen in infants and children. It is almost always unilateral and slightly more frequent in
boys and on the left side. The other associated extra-renal abnormalities include esophageal atresia,
tracheoesophageal atresia, ventricular septal defect and patent ductus arteriosus. The routine widespread
use of antenatal ultrasonography has led to early detection of this abnormality.
Materials and Methods: We retrospectively assessed fourteen cases of Multicystic dysplastic kidney
between January 2004 and December 2014. All the cases underwent total nephrectomy and the specimens
were sent to the department of Pathology with their respective clinical details and pathological findings
were analyzed.
Results: A total of fourteen (14) patients were diagnosed with unilateral MCDK over a period of 10
years with no sex predilection. Majority were on left side and antenatally diagnosed. Some patients had
associated hypertension, vesicoureteral reflux and ureteropelvic junction obstruction. Microscopy revealed
renal parenchyma replaced by cysts of variable sizes lined by flattened cuboidal epithelium. Intervening
fibrotic stroma with mesenchymal components, primitive glomeruli, nerve bundles and dysplastic ducts.
Conclusion: MCDK is mostly a unilateral sporadic anomaly usually found on the left side, however
can be familial. It may be associated with hypertension, vesicoureteral reflux and ureteropelvic junction
obstruction. Most of the patients can be diagnosed antenatally and confirmed on histopathology.

Keywords: Multicystic dysplastic kidney, Dysplastic kidney, Cystic kidney.


Doi : 10.18231/j.achr.2019.041

How to cite : Sowmya B U, Nandish V S, Saldanha P, Multicystic dysplastic kidney: Ten-year evaluation. IP Arch Cytol Histopathol Res 2019;4(3):216-219

Copyright © 2019 by author(s) and IP Arch Cytol Histopathol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (