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Current Opinion in Virus and Infectious Diseases - COVID


Status of hydroxychloroquine: COVID disease management protocol


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Article Type : Review Article

Author Details: S S Jha*

Volume : 1

Issue : 1

Online ISSN : XXXX XXXX

Print ISSN : XXXX XXXX

Article First Page : 6

Article End Page : 10


Abstract

Hydroxychloroquine, a safe derivative of chloroquine has been in practice since 1950. This drug has been used successfully as anti-viral agent previously. Its role in COVID-2 has been authenticated in the management protocol. The sudden death assigned to hydroxychloroquine is misplaced though it can be a very uncommon complication in cardiac patients with arrhythmia. Its prophylactic and therapeutic dose schedule needs to be streamlined at a lower dose schedule and is recommended to be used in early part of the disease and not during the stage of later complication.

Keywords: Hydroxychloroquine, Arrhythmia, Pathogen, Host target cell, ACE-2, Intracellular.

Doi No:-10.18231/j.ijirm.2020.017