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International Dental Journal of Student Research


A well differentiated oral squamous cell carcinoma involving the lateral border of tongue- A unique case report


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Case Report

Author Details : Sharmila M*, Saravanan I, Vivekanandan U, Gonala Krishnan S, Gomathi GD

Volume : 7, Issue : 4, Year : 2019

Article Page : 121-124


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Abstract

Oral cancer is the 6th commonest among all the malignancies, affecting more than half a million people each year, with a reported of 75000-80000 new cases annually in India. Among other Head and Neck malignancies, 95% of cases accounts for oral squamous cell carcinomas. According to the surveillance, Epidemiology and End results program stated that the relative prognosis rate of 62.2% is given with an overall period of 5 years. Oral squamous cell carcinoma is before to specific potentially malignant disorders, of which the most common ones are Oral leukoplakia and OSMF due to a well-known risk factors like consumption of tobacco, arecanut and alcohol. Other factors include age and family history of cancer, HPV infections, immunosuppression, UV light and some hereditary associated conditions etc. According to WHO prognosticate by 2020, the tobacco-related deaths may exceeds 1.5 million per year. Several epidemiological studies showed that smokers tends to prosper oral cancer 5-9 times than non-smokers. This case report describes a well-differentiated oral squamous cell carcinoma involving the left lateral border of tongue.

Keywords: OSCC (Oral Squamous Cell Carcinoma), OSMF (Oral Submucous Fibrosis), EGFR (Epithelial Growth Factor Receptor), LOH (Loss of Heterozygosity), CGH (Comparative Genomic Hybridization).

Doi : 10.18231/j.idjsr.2019.028

How to cite : Sharmila M, Saravanan I, Vivekanandan U, Gonala Krishnan S, Gomathi Gd, A well differentiated oral squamous cell carcinoma involving the lateral border of tongue- A unique case report. Int Dent J Stud Res 2019;7(4):121-124

Copyright © 2019 by author(s) and Int Dent J Stud Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)