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International Dental Journal of Student Research

Oral leukoplakia: risk of malignant transformation and the importance of surgical excision

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Author Details : Mariem Meddeb, Abdellatif Chokri, Faten Hammedi, Karim Masmoudi, Hajer Hentati, Jamil Selmi

Volume : 4, Issue : 3, Year : 2016

Article Page : 123-127

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Leukoplakia is the most frequent potentially malignant lesion of the oral mucosa. Its diagnostic and therapeutic present a challenge for dentist. Two clinical cases of oral leukoplakia were reported. The first was a patient using chewed tobacco consulted for a verrucous oral lesion that was surgically completely removed. Histopathological examination of the specimen revealed verrucous carcinoma. The second was a smoker man presenting an oral leukoplakia with fungal infection. After antimycotic treatment and periodic follow up, the clinical signs of candidiasis regressed but the mucosal white patch persisted. A large part of the lesion was removed. Histopathological examination indicated a well-differentiated squamous cell carcinoma.

Leukoplakia, Oral mucosa, Biopsy, Dysplasia, Carcinoma

How to cite : Meddeb M, Chokri A, Hammedi F, Masmoudi K, Hentati H, Selmi J, Oral leukoplakia: risk of malignant transformation and the importance of surgical excision. Int Dent J Stud Res 2016;4(3):123-127

Copyright © 2016 by author(s) and Int Dent J Stud Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (