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IP Indian Journal of Anatomy and Surgery of Head, Neck and Brain

A huge ossifying Fibromyxoid tumor of maxilla causing mandibular bowing - A rare case report with review of literature

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Author Details : Ashwin Ashok Jaiswal, Aditi Sharma, Girish Umredkar, A K Garg, Ravindranath Membally

Volume : 3, Issue : 4, Year : 2017

Article Page : 118-123

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Ossifying Fibromyxoid Tumor (OFMT) is a rare soft-tissue neoplasmof uncertain origin that occurs usually in the subcutaneoustissue of the extremities. Head and neck involvement is relatively rare and its occurrence in oral cavity is extremely rare. We, herein, present a case of 40 yrs female patient with a huge (approx10 x 8cm in size), Solitary, Globular, painless swelling over right side of face since six years. FNAC showed spindle cells to ovoid cells in a myxoid background.Computed Tomography scan was suggestive of A Large globular mixed density mass over the alveolar margin of right upper alveolus with extensive calcification with bowing of the mandible. A punch biopsy was done which on microscopic examination revealed Subepithelium tissue showing spindle cells with moderate pleomorphism in a fibromyxoid background creating a possibility of fibromyxoid tumor. Complete excision of the tumour with right partial maxillectomy was done. The histopathological examination of the excised specimen showed extensive ossification rimmed by osteoblast in the periphery of tumor suggesting ossifying fibromyxoid tumour. On Immunohistochemistry the tumour tissue was found to be strongly positive for vimentin whereas Ki67 was positive in <1 % providing a low proliferative index thus confirming the diagnosis of Typical OFMT.The patient demonstrated no evidence of local recurrence till 2 years of follow-up.

Keyword: Ossifying Fibromyxoid Tumor (OFMT), FNAC, Computed Tomography, Immunohistochemistry

How to cite : Jaiswal A A, Sharma A, Umredkar G, Garg A K, Membally R, A huge ossifying Fibromyxoid tumor of maxilla causing mandibular bowing - A rare case report with review of literature. IP Indian J Anat Surg Head Neck Brain 2017;3(4):118-123

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