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Indian Journal of Clinical Anaesthesia


Comparison of intrathecal Tramadol and Magnesium sulfate as an adjuvant to Levobupivacaine in mild Pre-eclamptic parturients undergoing caesarean section A prospective randomized control study


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Research Article

Author Details : Aditi A Dhimar*, Vallary Modh, M R Upadhyay

Volume : 6, Issue : 4, Year : 2019

Article Page : 481-487


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Abstract

Aims and Objective: Spinal anaesthesia is advantageous as compare to general anaesthesia for cesarean
section especially in preeclampsia as it avoids the complications of general anaesthesia. To improve the
quality of sensory and motor blockade and prolong the duration of postoperative analgesia, we had used
tramadol and magnesium sulfate intrathecally with the primary aim to assess sensory and motor blockade
and postoperative analgesia.
Material and Methods: This prospective randomized control study included sixty preeclamptic parturient
having more than 36 weeks of pregnancy with controlled hypertension aged 18-40 years with single
pregnancy, planned for caesarean section of ASAPS II, III and able to understand VAS score were included.
Parturients were randomly assigned to g roup LT (injection Levobupivacaine 0.5%, 1.5ml + injection
Tramadol 25 mg,0.5ml) and group LM (injection Levobupivacaine 0.5%, 1.5ml + injection Magnesium
sulfate 100 mg,0.5ml) using computer generated random numbers and the assignment was sealed in
envelopes for concealment. They were assessed for sensory blockade, motor blockade and postoperative
analgesia.
Results: The onset of sensory block was late in group LM [102sec (102-105) sec] in comparison to group
LT [69sec (66-72) sec, P<0> 2) min] in comparison to group LT [1.6min (1.5-1.6) min, P<0> in group LM [93.5sec (92-95) sec] compared to group LT [60sec (58-63) sec, P<0> of post-operative analgesia was extended further for group LM [570min (540-600) min], in comparison to
group LT [357min (342-360) min, P<0> Conclusion: Intrathecal magnesium sulfate can be considered as a desirable adjuvant to Levobupivacaine
in mild preeclamptic parturients undergoing cesarean section compared to tramadol.

Keywords: Intrathecal, Levobupivacaine, Magnesium sulfate, Preeclampsia, Tramadol.

Doi : 10.18231/j.ijca.2019.094

How to cite : Dhimar A A, Modh V, Upadhyay M R, Comparison of intrathecal Tramadol and Magnesium sulfate as an adjuvant to Levobupivacaine in mild Pre-eclamptic parturients undergoing caesarean section A prospective randomized control study. Indian J Clin Anaesth 2019;6(4):481-487

Copyright © 2019 by author(s) and Indian J Clin Anaesth. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)