COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804

Article view: 188

Article download: 116

Indian Journal of Clinical Anaesthesia


Intranasal midazolam: Sedation for radiological procedures


Full Text PDF Share on Facebook Share on Twitter


Research Article

Author Details : Daxa Hiren Oza*, Vaibhavi Patel, Priya Pathak, Rahul C Manek, Miunalini G Patel

Volume : 6, Issue : 4, Year : 2019

Article Page : 493-496


Suggest article by email

Abstract

Context: Preoperative stress, anxiety and lack of cooperative ability of paediatric patients need sedation
for radiological procedure.
Aims: The purpose of study is to compare and evaluate efficiency and safety of two doses of intranasal
midazolam.
Settings and Design: This is a prospective Randomized controlled study of interventional type of study.
Methods and Material: Sixty patient of age 1 to 4 years, ASA 1 and ASA2 undergoing radiological
procedure were randomly divided into two groups. Group A received 0.3 mg/kg and Group B received
0.5 mg/kg of intranasal spray of midazolam. Sedation score, haemodynamic variations, ease of separation,
Venepunture response and side effect were studied.
Statistical analysis used: Data analysis was performed using SPSS for Windows, version 20.0(SPSS Inc.,
Chicago, IL)
Results: Higher sedation score achieved earlier with 0.5mg/kg dose, Parenteral separation and IV line
insertion was more easier with 0.5 mg/kg dose but recovery slight delay compare to 0.3 mg/kg dose after
20 min of procedure completion but there was no much prolongation of recovery time, at 30 min of all
patient discharged in both groups.
Conclusions: High Sedation score, parentral separation and response to IV line was earlier and easier with
0.5 mg/kg dose.
Key Messages: Intranasal Midazolam is safe and effective as sedative in paediatric radiological procedure.

Keywords: Intranasal, Midazolam, Radiological procedure.

Doi : 10.18231/j.ijca.2019.096

How to cite : Oza D H, Patel V, Pathak P, Manek R C, Patel M G, Intranasal midazolam: Sedation for radiological procedures. Indian J Clin Anaesth 2019;6(4):493-496

Copyright © 2019 by author(s) and Indian J Clin Anaesth. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)