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Indian Journal of Clinical Anaesthesia

To compare the efficacy of oral aspirin vs intravenous diazepam on succinylcholine induced postoperative myalgia

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Research Article

Author Details : Ramesh R, Kantharaja H E*, Sushma P, Dayanand V P

Volume : 6, Issue : 4, Year : 2019

Article Page : 508-512

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Introduction: Succinylcholine is a short acting neuromuscular blocking age nt.. It has its own side effects
which includes dysrhythmias, hyperkalemia, postoperative myalgias, etc. The incidence of muscle pain
ranges from 0.2 to 89% and thus the need for the study.
Materials and Methods: 60 adult patients are included in this prospective , randomised , double blind
study who are scheduled to undergo elective surgery under general anaesthesia. Two groups were made
randomly and Patients received either oral aspirin 600mg one hour before surgery or intravenous diazepam
fifteen minutes before induction. Appropriate statistical tests were applied.
Results: Status of muscle pain was recorded at 1st , 6th, 12th and 24th post operative period. Myalgia at 6th,
12th and 24th hour was significantly reduced in aspirin group compared to diazepam group. No difference
was seen at one hour.
Conclusion: It was concluded that aspirin prevents succinylcholine induced myalgia more effectively than
diazepam in postoperative period.

Keywords: Aspirin, Diazepam, Myalgia, Succinyl choline.

Doi : 10.18231/j.ijca.2019.099

How to cite : Ramesh R, Kantharaja H E, Sushma P, Dayanand V P, To compare the efficacy of oral aspirin vs intravenous diazepam on succinylcholine induced postoperative myalgia. Indian J Clin Anaesth 2019;6(4):508-512

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