Print ISSN:-2394-4781

Online ISSN:-2394-4994


Current Issue

Year 2020

Volume: 7 , Issue: 2

Article Access statistics

Viewed: 107

Emailed: 0

PDF Downloaded: 80

Indian Journal of Clinical Anaesthesia

A comparative evaluation of intranasal dexmedetomidine with and without nalbuphineas premedication for pediatric dental patients

Full Text PDF Share on Facebook Share on Twitter

Research Article

Author Details : S K Sonker, K P Mall*, Sujeet Rai

Volume : 7, Issue : 1, Year : 2020

Article Page : 117-122

Suggest article by email


Introduction: Management of children’s fear and anxiety during treatment is a primary concern of
paediatric dental practitioners. There are a number of children who are difficult to be managed by basic
behaviour guidance techniques.
Objective: To evaluate the safety and efficacy of intranasal Dexmedetomidine with and without Nalbuphine
procedural sedation in paediatric dental patients.
Materials and Methods: This study was conducted in Department of Pedodontics and Preventive
Dentistry, Babu Banarasi Das College of Dental Sciences Lucknow in collaboration with Department of
Pharmacology, King George Medical University Lucknow. Ninety six systemically healthy children (ASA
type I) between 4-8 years of age for whom basic behaviour modification techniques were not successful in
providing dental treatment were included in the study. Each parent/guardian was requested to fill a written
informed consent form at the initial appointment. Data analysis was carried out using SPSS 16.0 version.
Result: Considering the efficacy parameter (duration, time of recovery) the intranasal dexmedetomidine
(group 1, 2.5 mg/ kg) was found to be the better for procedural sedation. Intranasal administration with
atomizer and nasal drop had no significant difference.
Conclusion: Intranasal dexmedetomidine alone and in combination with nalbuphine showed comparable
sedative efficacy with no additional advantage of combination over dexmedetomidine alone. Use of a
commercially available atomizer showed improved patient’s acceptance of intranasal administered drugs
but did not influence efficacy as compared to nasal drops.

Keywords: Nasal drop, Atomizer, Nalbuphine.

Doi : 10.18231/j.ijca.2020.021

How to cite : Sonker S K, Mall K P, Rai S, A comparative evaluation of intranasal dexmedetomidine with and without nalbuphineas premedication for pediatric dental patients. Indian J Clin Anaesth 2020;7(1):117-122

Copyright © 2020 by author(s) and Indian J Clin Anaesth. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (