COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details.,, Mob. 8826373757, 8826859373, 9910947804

Print ISSN:-2394-4781

Online ISSN:-2394-4994


Current Issue

Year 2020

Volume: 7 , Issue: 1

Article Access statistics

Viewed: 586

Emailed: 0

PDF Downloaded: 213

Indian Journal of Clinical Anaesthesia

Comparison of intraperitoneal bupivacaine alone or with dexmedetomidine or tramadol for post operative analgesia following laparoscopic cholecystectomy

Full Text PDF Share on Facebook Share on Twitter

Author Details : Mukkavilli Lakshmi Narasimham, B. Dinakar Rao

Volume : 4, Issue : 1, Year : 2017

Article Page : 143-146

Suggest article by email


Introduction: This study was conducted to evaluate the effect of Intraperitoneal Bupivacaine alone or with dexmedetomidine or tramadol for relief of pain after laparoscopic cholecystectomy.
Material and Methods: The patients were divided into 3 Groups of 50 each, Group A was given 50 ml 0.25% bupivacaine and 5 ml normal saline, Group B 50ml 0.25% bupivacaine plus tramadol 1mg/kg wt and Group C, 50ml 0.25% bupivacaine plus dexmedetomidine 1ug/kg. The duration of analgesic effect was noted based on the time difference between the disappearance of pain after the analgesic injection and reappearance of pain was recorded and assessed by using VAS scale.
Results: The number of females were slightly more than the male. The age group of the patients predominantly ranged between 31-40 years. Pain was significantly lower in Group C i.e. patients given bupivacaine plus dexmedetomidine compared to the patients in Group A and Group B. Patients in Group A i.e. with bupivacaine alone had the highest VAS score. Post-surgery, minor complications were seen in a few patients, with nausea being most common, followed by vomiting and pruritis.
Conclusion: Bupivacaine plus dexmedetomidine given to patients who underwent laparoscopic cholecystectomies was more effective as an analgesic compared to Bupivacaine alone or in combination with Tramadol.

Bupivacaine, Dexmedetomidine, Tramadol, Analgesics, Comparison

How to cite : Narasimham M L, Rao B D, Comparison of intraperitoneal bupivacaine alone or with dexmedetomidine or tramadol for post operative analgesia following laparoscopic cholecystectomy. Indian J Clin Anaesth 2017;4(1):143-146

Copyright © 2017 by author(s) and Indian J Clin Anaesth. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (