COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details.,, Mob. 8826373757, 8826859373, 9910947804

Print ISSN:-2394-4781

Online ISSN:-2394-4994


Current Issue

Year 2020

Volume: 7 , Issue: 1

Article Access statistics

Viewed: 831

Emailed: 0

PDF Downloaded: 227

Indian Journal of Clinical Anaesthesia

Comparison of 5µg and 10 µg of Dexmedetomidine as an adjuvant with Bupivacaine (heavy) under Spinal anaesthesia in Urological surgeries

Full Text PDF Share on Facebook Share on Twitter

Author Details : Mahadeva Prasad DR, Anitha Hanji S, Narasimha Gnani BC

Volume : 4, Issue : 3, Year : 2017

Article Page : 324-328

Suggest article by email


Objectives: This study is to know the efficacy of 5µg and 10µg of Dexmedetomidine adding to 0.5% bupivacaine (heavy) under spinal anaesthesia for urological procedures.
The purpose of our study is to know sensory onset, motor onset, sensory blockade duration, motor blockade duration, effective analgesia duration, rescue analgesia duration, VAS score, haemodynamic factors like heart rate and blood pressure and also untowards adverse effects.
Materials and Method: In a prospective randomized study, 120 patients of ASA grade I/II aged between 20 - 60 years undergoing urological surgeries were divided randomly into three groups of 40 each. Group D5- 0.5% hyperbaric bupivacaine 12.5 mg (2.5ml) + 5 µg Dexmedetomidine, Group D10- 0.5% hyperbaric bupivacaine 12.5 mg (2.5ml) + 10 µg Dexmedetomidine, Group BS- 0.5% hyperbaric bupivacaine 12.5mg + normal saline 0.5ml. Results was analysed using one way ANOVA and Kruskal wallis test. p<0.05 considered statistically significant.
Results: In Dexmedetomidine groups sensory and motor blockade onset was early (Group D10>Group D5). Sensory blockade duration and motor blockade duration was increased. Effective and rescue analgesia duration was also increased in the order of GroupD10>Group D5>Group BS. There was no clinically significant haemodynamic parameters alteration without any adverse effects/complication among three groups.
Conclusion: 10µg dexmedetomidine enhances the duration of analgesia and patients remained pain free for a longer period of duration in post-operative period compared to plain bupivacaine or 5µg dexmedetomidine with better haemodynamic stability with minimal or no adverse effects.


How to cite : Mahadeva Prasad Dr, Anitha Hanji S, Narasimha Gnani Bc, Comparison of 5µg and 10 µg of Dexmedetomidine as an adjuvant with Bupivacaine (heavy) under Spinal anaesthesia in Urological surgeries. Indian J Clin Anaesth 2017;4(3):324-328

Copyright © 2017 by author(s) and Indian J Clin Anaesth. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (