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Indian Journal of Clinical Anaesthesia

Comparison of efficacy of Nebulized ketamine versus lignocaine for postoperative sorethroat

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Research Article

Author Details : P Ramadevi*, E Shanmugavalli

Volume : 6, Issue : 3, Year : 2019

Article Page : 406-409

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Introduction: Post operative sore throat (POST) is a common post operative complaint following general anaesthesia with endotracheal intubation. Its incidence ranges from 30-75%. It may cause significant post operative morbidity and patient dissatisfaction.
Aim: The aim of the study is to evaluate the efficacy of ketamine and lignocaine nebulization.
Materials and Methods: This study is a Prospective randomised control study. After obtained Institutional Ethical Committee approval and written informed consent, 90 adult patients were randomized into three groups each consists of 30 participants. Group K received ketamine 50mg with 4ml of normal saline, Group B received lignocaine 2% 2ml with 2ml of normal saline nebulization 15 mins before induction and Group C did not receive any nebulization and is a control group.Postoperative sorethroat was monitored based on four point scale at immediate, 2, 4, 8, 12 and 24 hrs.
Results: The Severity of postoperative sorethroat was less in lignocaine and ketamine group compared to control group.On follow up for 24 hours, ketamine group provides better relief in sorethroat compared to lignocaine group.Hemodynamic parameters were comparable in all three groups.
Conclusion: Ketamine nebulization and lignocaine nebulization provides less discomfort to the patient and the severity of sore throat was less over 24 hrs in the post operative period. To conclude ketamine nebulization provides better relief of post operative sore throat when compared to lignocaine nebulization and no nebulization.

Keywords: Lignocaine, Ketamine, Sorethroat, Nebulization.

Doi : 10.18231/j.ijca.2019.078

How to cite : Ramadevi P, Shanmugavalli E, Comparison of efficacy of Nebulized ketamine versus lignocaine for postoperative sorethroat. Indian J Clin Anaesth 2019;6(3):406-409

Copyright © 2019 by author(s) and Indian J Clin Anaesth. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (