COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details.,, Mob. 8826373757, 8826859373, 9910947804

Print ISSN:-2394-2118

Online ISSN:-2394-2126


Current Issue

Year 2020

Volume: 7 , Issue: 1

Article Access statistics

Viewed: 665

Emailed: 0

PDF Downloaded: 203

Indian Journal of Clinical Anatomy and Physiology

Evaluation of diuretic activity of Lagenaria Siceraria in Albino rats

Full Text PDF Share on Facebook Share on Twitter

Author Details : K. Harini, T. Jayasree

Volume : 2, Issue : 3, Year : 2017

Article Page : 99-103

Suggest article by email


Lagenaria siceraria belongs to Cucurbitaceae family. It is commonly known as lauki (Hindi) and bottle gourd (English) is a medicinal plant. It is used as medicine for its cardio tonic, general tonic and diuretic properties.
The present study was aimed to evaluate the diuretic activity of Lagenaria siceraria in comparison to Hydrochlorothiazide. 5 groups of rats with 6 rats in each group were taken.1st group of 6 rats was kept as control. 2nd group of 6 rats were fed with standard hydrochlorothiazide. The Third, fourth and fifth groups of 6 rats each were taken as test groups and administered with the crude extract of LAGENARIA SICERARIA in doses of 100, 200 and 400mg/kg body weight. The urine was collected for a period of 5 hours and 24 hours. Urinary volume, urinary electrolytes namely sodium, potassium and chloride are estimated.
The results obtained in the study indicate that Aqueous Extract of Lagenaria siceraria(AELS) increases the excretion of 3 parameters i.e. urinary volume, urinary Na+, urinary Cl- which is statistically significant and comparable to that of the standard diuretic agent hydrochlorothiazide and decrease K+excreation.

Lagenaria siceraria, Hydrochlorothiazide, Diuretic activity, Urinary volume, Urinary Na+, k+, Cl- excretion

How to cite : Harini K, Jayasree T, Evaluation of diuretic activity of Lagenaria Siceraria in Albino rats. Indian J Clin Anat Physiol 2017;2(3):99-103

Copyright © 2017 by author(s) and Indian J Clin Anat Physiol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (