COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details.,, Mob. 8826373757, 8826859373, 9910947804

Article view: 202

Article download: 144

Indian Journal of Clinical Anatomy and Physiology

Effect of smoking on visual evoked potential

Full Text PDF Share on Facebook Share on Twitter

Research Article

Author Details : Kavyashree H M*, Deshpande D V, Prashanth Sripuram, Sindhuja A

Volume : 6, Issue : 3, Year : 2019

Article Page : 309-314

Suggest article by email


Introduction: The relationship of smoking with visual evoked potential is debated. Cigarette smoke
contains cytotoxic compounds which directly or indirectly cause damage to neuronal cells. Smokers
develop elevated carboxyhaemoglobin levels which might impair function of central nervous system by
affecting oxygen transport and its utilization leading to perceptual-motor delay in smokers.
Objectives: To record the visual evoked potential in smokers and non-smokers aged 20-40years and to
compare between two groups for any changes in P100.
Materials and Methods: Age matched 100 male smokers and 100 male non smokers in the age group of
20-40 years were studied for visual evoked potential. Smoking in terms of pack years was noted. Data was
statistically analyzed.
Results: Visual evoked potential was affected in smokers with prolongation of latency and decrease in
amplitude of P100 in both the eyes than non smokers, with is statistically highly significant. There is a
significant positive correlation between smoking history expressed in pack-years and latency of P100 in
smokers group.
Conclusion: Smoking causes degeneration in optic nerve shown by increased latency of P100 which
increases as the number of pack-years increase.

Keywords: Smoking, Pack years, Visual evoked potential, P100.

Doi : 10.18231/j.ijcap.2019.068

How to cite : Kavyashree H M, Deshpande D V, Sripuram P, Sindhuja A, Effect of smoking on visual evoked potential. Indian J Clin Anat Physiol 2019;6(3):309-314

Copyright © 2019 by author(s) and Indian J Clin Anat Physiol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (