COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details.,, Mob. 8826373757, 8826859373, 9910947804

Article view: 32

Article download: 20

International Journal of Clinical Biochemistry and Research

Evaluation of thyroid profile in active and passive smokers

Full Text PDF Share on Facebook Share on Twitter

Research Article

Author Details : Tapaswini Pradhan, Sumit Jhajharia*, Kavita Aggarwal

Volume : 7, Issue : 1, Year : 2020

Article Page : 62-64

Suggest article by email


Tobacco has multiple effects on the hypothalamic-pituitary-thyroid axis and the functioning of the thyroid
gland. The adverse mechanisms of smoke exposure include alteration of thyroid hormone synthesis,
binding, transport, storage and clearance, thereby resulting in changes in the circulating hormone
concentrations. This study was designed to analyze the effect of smoking on thyroid profile, measuring
serum TSH, total T3 and total T4 levels in active and passive smokers. The results revealed that both active
and passive smokers had highly significant decreased serum total T3 and T4 levels along with substantially
increased serum TSH levels in comparison to non-smokers (p < 0> status between the both case groups was less statistically significant (p < 0> nature of tobacco smoke on the activity of thyroid, irrespective of its nature and origin.

Keywords: Thyroid profile, Active and passive smokers.

Doi : 10.18231/j.ijcbr.2020.013

How to cite : Pradhan T, Jhajharia S, Aggarwal K, Evaluation of thyroid profile in active and passive smokers. Int J Clin Biochem Res 2020;7(1):62-64

Copyright © 2020 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (