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International Journal of Clinical Biochemistry and Research


Evaluation of thyroid profile in active and passive smokers


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Research Article

Author Details : Tapaswini Pradhan, Sumit Jhajharia*, Kavita Aggarwal

Volume : 7, Issue : 1, Year : 2020

Article Page : 62-64


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Abstract

Tobacco has multiple effects on the hypothalamic-pituitary-thyroid axis and the functioning of the thyroid
gland. The adverse mechanisms of smoke exposure include alteration of thyroid hormone synthesis,
binding, transport, storage and clearance, thereby resulting in changes in the circulating hormone
concentrations. This study was designed to analyze the effect of smoking on thyroid profile, measuring
serum TSH, total T3 and total T4 levels in active and passive smokers. The results revealed that both active
and passive smokers had highly significant decreased serum total T3 and T4 levels along with substantially
increased serum TSH levels in comparison to non-smokers (p < 0> status between the both case groups was less statistically significant (p < 0> nature of tobacco smoke on the activity of thyroid, irrespective of its nature and origin.

Keywords: Thyroid profile, Active and passive smokers.

Doi : 10.18231/j.ijcbr.2020.013

How to cite : Pradhan T, Jhajharia S, Aggarwal K, Evaluation of thyroid profile in active and passive smokers. Int J Clin Biochem Res 2020;7(1):62-64

Copyright © 2020 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)