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International Journal of Clinical Biochemistry and Research


Evaluation of performance of Lipid Accumulation Product (LAP), an obesity index as a marker for diagnosing overt type 2 diabetes mellitus over Body Mass Index (BMI)


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Author Details : Nirmitha Dev. M, Krishnamurthy U

Volume : 3, Issue : 4, Year : 2016

Article Page : 426-428


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Abstract

Objectives of the study: To compare the indices available to measure obesity such as BMI and “lipid accumulation product” (LAP) with respect to risk for development of Type-II Diabetes mellitus.    
Methodology: The study design was cross sectional with sample size of 120. Anthropometric measurements (BMI and LAP) and biochemical estimations (blood glucose & lipid profile) were carried out.
Results: We compared the values of LAP and BMI with Fasting blood glucose. The area under the curve was 0.75 and 0.73 respectively which meant LAP was better in identification of overt Type 2 Diabetes. The cut off for BMI is 25.98 with Sensitivity of 0.83, Specificity of 0.64 & youden index 0.47. The cut off for LAP is 50.79 with Sensitivity of 0.79, Specificity of 0.68 & youden index 0.46.
Conclusion: LAP was able to identify the risk for type 2 Diabetes better compared with BMI in our study subjects.

How to cite : Nirmitha Dev. M, Krishnamurthy U, Evaluation of performance of Lipid Accumulation Product (LAP), an obesity index as a marker for diagnosing overt type 2 diabetes mellitus over Body Mass Index (BMI). Int J Clin Biochem Res 2016;3(4):426-428

Copyright © 2016 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)