COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804


Print ISSN:-2394-6369

Online ISSN:-2394-6377

CODEN : IJCBK6

Current Issue

Year 2020

Volume: 7 , Issue: 1

Article Access statistics

Viewed: 678

Emailed: 0

PDF Downloaded: 186

International Journal of Clinical Biochemistry and Research


Prevalence of Haemoglobinopathies in Punjabi population


Full Text PDF Share on Facebook Share on Twitter


Author Details : Anju Sharma, Neha, Sahiba Kukreja, Jaskiran Kaur, Amandeep Kaur

Volume : 4, Issue : 1, Year : 2017

Article Page : 43-46


Suggest article by email


Abstract

Background: The prevalence of thalassemias and various hemoglobinopathies are a major public health problem in Punjabi population. These cases are mainly overlooked and thus only treated as a part of anaemia. Thus it is worthwhile to study its prevalence and occurrence. The main objective of our study was to find the prevalence of hemoglobinopathies in Punjab and implement strategies for preventing marriages between two carriers for effective control of these diseases.
Material and Methods: This was a case control retrospective study for screening for haemoglobinopathies of patient samples collected in biochemistry clinical laboratory, SGRDIMSAR, Vallah, Amritsar from 1 June 2015 to 30 May 2016 using automated Interlab Genios S electrophoresis system. EDTA samples were collected and 30 µL of lysate was applied on Genios S electrophoresis system in alkaline haemoglobin buffer. The results were interpreted by densitometer were obtained as a graph and interpreted.
Results: In this study, out of 187 samples we received for screening of haemoglobinopathies, total of 143 (78.5%) were found to have a normal electrophoretic pattern and 44 patients (21.4%) were found to have one or other form of hemoglobinopathy.
Conclusion: Punjabi population has high prevalence of haemoglobinopathy screening being an affordable and accessible way to detect carriers, it should be made mandatory in high schools, before marriage and antenatal clinics. Also, public education and awareness for screening in areas of high prevalence of consanguinity should be made mandatory.

How to cite : Sharma A, Neha, Kukreja S, Kaur J, Kaur A, Prevalence of Haemoglobinopathies in Punjabi population. Int J Clin Biochem Res 2017;4(1):43-46

Copyright © 2017 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)