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International Journal of Clinical Biochemistry and Research

A comparative study of glucose concentration determined from venous plasma sample and capillary blood sample

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Author Details : Ayaz Khurram Mallick, Marya Ahsan

Volume : 4, Issue : 3, Year : 2017

Article Page : 220-224

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Context: Self-monitoring of glucose levels with a hand held glucometer is very popular among the diabetic patients and doctors as it is less traumatic and gives instant results. Capillary blood samples are commonly used for self-monitoring in comparison to venous plasma sample which are used in the diagnostic laboratories.
Aims: This study was done to compare the glucose levels of a capillary blood sample determined by a glucometer with the glucose level determined by Glucose Oxidase Peroxidase (GOD-POD) method using a venous plasma sample.
Setting and Design: This experimental study was carried out at Rohilkhand Medical College and Hospital.
Methods and Material: Two hundred patients were randomly selected for the study. Their venous blood samples were collected in a fluoride containing blood collection tube. The plasma obtained was subjected to GOD-POD test. Simultaneously their capillary blood glucose was also determined by a glucometer.
Statistical analysis used: The data collected was analyzed using SPSS 17.0 version. Data was expressed as mean ± SD. Significance of mean was analyzed using paired t test. P value < 0.05 was considered significant.
Result: Glucose levels determined by a glucometer and GOD-POD method showed very good correlation (r=0.958; p<0.001). However, at very high and low glucose levels, the glucometer significantly under estimated (p=0.014) and over-estimated (p<0.001) the glucose levels respectively.
Conclusion: Although glucometers are effective for routine monitoring of glucose levels, they should be used cautiously in emergency conditions.

Glucose levels, GOD-POD method, Glucometer

How to cite : Mallick A K, Ahsan M, A comparative study of glucose concentration determined from venous plasma sample and capillary blood sample. Int J Clin Biochem Res 2017;4(3):220-224

Copyright © 2017 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (