COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details.,, Mob. 8826373757, 8826859373, 9910947804

Print ISSN:-2394-6369

Online ISSN:-2394-6377


Current Issue

Year 2020

Volume: 7 , Issue: 1

Article Access statistics

Viewed: 652

Emailed: 0

PDF Downloaded: 290

International Journal of Clinical Biochemistry and Research

Analysis of serum ferritin levels in non-diabetic, prediabetic and diabetic individuals

Full Text PDF Share on Facebook Share on Twitter

Author Details : Chandrika N., Usha S.M.R.

Volume : 5, Issue : 1, Year : 2018

Article Page : 1-4

Suggest article by email


Introduction: Type 2 diabetes mellitus (T2DM) is characterized by impaired insulin secretion, insulin resistance or both. In the initial asymptomatic phase there is hyperinsulinemia, as insulin resistance progress and beta cell function deteriorates ‘Prediabetes’ an intermediate hyperglycemic state prone for diabetic complications ensues. A chronic sub-clinical inflammation is associated with insulin resistance and it can be assessed using a pro-inflammatory marker like serum ferritin.
Aim: We intend to evaluate serum ferritin levels in normoglycemics, intermediate hyper glycemics and overt cases of T2DM and also to investigate if any correlation exists between blood glucose and serum ferritin levels at these three different stages of glycemia.
Materials and Methods: In accordance with World health organisation guidelines, we inducted forty seven pre-diabetics and thirty seven T2DM patients in the first and second groups of our study respectively. Twenty three healthy controls constituted the third group. Serum ferritin, fasting and 2 hour postprandial blood glucose were estimated in all subjects.
Results: The mean ± SD of Log serum ferritin levels in prediabetic, diabetic group and Controls groups are 4.21±0.96, 4.25±1.07 and 3.59±0.95µg/L respectively. Mean Log serum ferritin levels is significantly higher in pre-diabetics and diabetics with p=0.012. A positive and statistically significant association was noticed between serum ferritin and blood glucose levels when the subjects of the three groups were considered together (p=0.036) but not when the groups were considered separately.
Conclusion: Serum ferritin levels are elevated in prediabetes and T2DM when compared to healthy controls and it reflects the inflammation associated with prediabetes and T2DM.

Keywords: Blood glucose, Inflammation, Prediabetes, Serum ferritin, Type 2 diabetes mellitus.

Doi : 10.18231/2394-6377.2018.0001

How to cite : Chandrika N., S.m.r. U, Analysis of serum ferritin levels in non-diabetic, prediabetic and diabetic individuals. Int J Clin Biochem Res 2018;5(1):1-4

Copyright © 2018 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (