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International Journal of Clinical Biochemistry and Research


Degradation of Spectrin and band 3 protein


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Author Details : Manisha G. Audi

Volume : 5, Issue : 2, Year : 2018

Article Page : 206-208


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Abstract

Oxygen free radicals generated during radiation injury damage human erythrocyte membrane proteins including spectrin and band 3 protein. Results show an appreciable degree of spectrin and band 3 protein loss of about 55-65% due to crosslinking, and proteolysis when sodium dodecyl sulphate polyacrylamide gel electrophoresis carried out on erythrocyte ghosts. Oxidative damage to membrane proteins lead to degradation of its cytoskeletal components.

Keywords: Spectrin, Band 3 protein, Erythrocyte ghosts, Oxygen free radicals

Doi : 10.18231/2394-6377.2018.0042

How to cite : Audi M G, Degradation of Spectrin and band 3 protein. Int J Clin Biochem Res 2018;5(2):206-208

Copyright © 2018 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)