COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details.,, Mob. 8826373757, 8826859373, 9910947804

Print ISSN:-2394-6369

Online ISSN:-2394-6377


Current Issue

Year 2020

Volume: 7 , Issue: 1

Article Access statistics

Viewed: 703

Emailed: 0

PDF Downloaded: 231

International Journal of Clinical Biochemistry and Research

Insight into the exocrine pancreatic function (serum amylase and lipase) in type 2 diabetes mellitus

Full Text PDF Share on Facebook Share on Twitter

Author Details : Manjula K. S., Reena R, Usha S.M.R., Priyadarshini K.S., H.V. Shetty

Volume : 5, Issue : 3, Year : 2018

Article Page : 379-382

Suggest article by email


Introduction: Insulin has its effect on the basal and stimulatory secretion of exocrine pancreatic enzymes. In this context this study has been done to understand the relationship between the exocrine and endocrine entities of pancreas by analyzing two most commonly estimated exocrine enzymes; serum amylase and serum lipase in type 2 DM.
Materials and Methods: The study was conducted at Rajarajeswari Medical College and Hospital, Bengaluru, Karnataka from January 2012 to December 2012. Hundred clinically diagnosed cases of type 2 diabetes mellitus {Fifty well controlled (HbA1c < 7>

Results: Serum amylase and serum lipase levels were within the reference range in all the three study groups. There was no significant difference in serum amylase among well controlled and poorly controlled type 2 DM. In contrast, significant difference in serum amylase levels was observed between diabetic group and controls (p<0> Conclusion: The potential underlying connection between exocrine and endocrine function of pancreas in patients with type 2 DM needs further investigation with larger population; to consider the analysis of serum pancreatic enzymes especially serum lipase levels as an additional informative parameter to assess the glycemic control in type 2 DM.

Keywords: Type 2 DM, Serum amylase, Serum lipase.

Doi : 10.18231/2394-6377.2018.0079

How to cite : Manjula K. S., Reena R, S.m.r. U, K.s. P, Shetty H, Insight into the exocrine pancreatic function (serum amylase and lipase) in type 2 diabetes mellitus. Int J Clin Biochem Res 2018;5(3):379-382

Copyright © 2018 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (