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Print ISSN:-2394-6369

Online ISSN:-2394-6377

CODEN : IJCBK6

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International Journal of Clinical Biochemistry and Research


Dendritic cells and vitamin D in dry eye disease


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Author Details : Balakrishnan .M, K. Sumathi, Pinky Karam, Rajarathinam

Volume : 5, Issue : 3, Year : 2018

Article Page : 431-434


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Abstract

To study the role of dendritic cells and vitamin D in troublesome evaporative dry eye diseases.
Materials and Methods: This is a cross sectional study which includes 108 patients having evaporative dry eye disease and 86 normal healthy volunteers. Ocular surface index, Shirmer’s test and tear film break up time, corneal dendritic cell density, vitamin D and cytokines in serum/tear were estimated. Vitamin D, cytokine in serum/tear and corneal dendritic cell density were estimated.
Result: Higher dendritic cell density noticed in evaporative dry eye disease patients compared to control group volunteers and revealed positive correlation with ocular surface index (P<0> Conclusion: Vitamin D has significant role in dry eye disease and its inflammation. Vitamin D therapy can be considered as an added treatment for dry eye disease.

Keywords: Dendritic cells, Vitamin D, Inflammatory cells, Dry eye.

Doi : 10.18231/2394-6377.2018.0091

How to cite : Balakrishnan .m, Sumathi K, Karam P, Rajarathinam, Dendritic cells and vitamin D in dry eye disease. Int J Clin Biochem Res 2018;5(3):431-434

Copyright © 2018 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)