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Print ISSN:-2394-6369

Online ISSN:-2394-6377

CODEN : IJCBK6

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International Journal of Clinical Biochemistry and Research


Studies on serum soluble endoglin: An indicator for preeclampsia


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Author Details : Archana A*, Brindha G, Ursula Sampson

Volume : 5, Issue : 4, Year : 2018

Article Page : 599-603


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Abstract

Introduction: To study the concentration of serum soluble endoglin during second trimester pregnancy and monitor for the development of preeclampsia.
Materials and Methods: Seventy-five healthy singleton pregnant women in second trimester was evaluated in this study. ELISA technique was used for measuring the concentration of Serum soluble endoglin. Patients with increased level of serum endoglin were monitored for signs and symptoms of preeclampsia.
Result: Thirty five pregnant women developed preeclampsia among 75 pregnant women. The mean value for sENG in cases was 8.7 ± 1.4 and control 5.9 ± 0.6. The normal value of serum sENG varies from 2.54 to 7.06 ng/ml. Hence, it is higher than the normal limit in cases.
Conclusions: The concentration of sENG was studied and women were monitored for development of preeclampsia. The present study showed that women with increased serum soluble endoglin levels developed preeclampsia later. Hence, it is suggested that soluble endoglin will be useful in predicting pre eclampsia.

Keywords: Endoglin, Preeclampsia, ELISA, sENG.

Doi : 10.18231/2394-6377.2018.0127

How to cite : Archana A, Brindha G, Sampson U, Studies on serum soluble endoglin: An indicator for preeclampsia. Int J Clin Biochem Res 2018;5(4):599-603

Copyright © 2018 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)