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International Journal of Clinical Biochemistry and Research


Role of C-reactive protein (CRP) in determining neonatal infections


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Research Article

Author Details : Chandrahas Godbole*, Poonam Lalla

Volume : 6, Issue : 3, Year : 2019

Article Page : 294-298


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Abstract

CRP is one of the reliable diagnostics marker used in diagnosis of Neonatal Sepsis that has been widely
available, most studied and preferred over the newly emerging infection markers. In this study, we have
studies that even CRP assay has proven to be less time consuming and effective analyzing samples of
neonates who are already on antibiotics treatment. In our study 40 neonates were proved to have neonatal
sepsis which was based on signs and symptoms shown by patient. The other studies have revealed, CRP
biochemistry assay have high sensitivity and specificity as compare to HSS for diagnosis of NS; we also
got 100% sensitivity and specificity for CRP testing. Hence we concluded that CRP is a good diagnostic
marker for the infection in neonates at the time of initial assessment. In our study we used quantitative
assay for CRP estimation which less time consuming and effective in analyzing samples of neonates who
are already on antibiotics treatment.

Keywords: CRP, C-reactive proteins, Neonatal Sepsis, Transasia, Erba, Pathology, Blood Culture, HSS, Neonatal Septicemia, Dr Godbole Laboratory, Pune, Signs of neonatal sepsis.

Doi : 10.18231/j.ijcbr.2019.065

How to cite : Godbole C, Lalla P, Role of C-reactive protein (CRP) in determining neonatal infections. Int J Clin Biochem Res 2019;6(3):294-298

Copyright © 2019 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)