COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804


Print ISSN:-2581-4710

Online ISSN:-2581-4729

CODEN : IIJCBS

Current Issue

Year 2020

Volume: 6 , Issue: 1

Article Access statistics

Viewed: 126

Emailed: 0

PDF Downloaded: 78

IP Indian Journal of Clinical and Experimental Dermatology


A clinico-aetiological study of fixed drug eruption amongst the patient attending tertiary care centre


Full Text PDF Share on Facebook Share on Twitter


Research Article

Author Details : Vivek Kumar Sahu, Bhaskar Gupta*

Volume : 5, Issue : 4, Year : 2019

Article Page : 332-335


Suggest article by email

Abstract

Introduction: Fixed drug eruption (FDE) is a cutaneous adverse drug reaction characterized by recurrent
well defined lesions occurring in the same sites each time the offending drug is taken. FDE typically
presents 30 min to 8 h after drug exposure. An extensive list of medications are known to cause FDE and
finding the underlying drug help in proper management of cases.
Aim: To study and analyse the causes and clinical pattern of FDE.
Materials and Methods: The study was performed in Silchar Medical College and Hospital, Silchar,
Assam. A total of 50 cases of FDE were studied. Cases of FDEs encountered between July 2018 to June
2019 during routine pharmacovigilance activities were analyzed.
Result: Among 50 patients, 34 were male and 16 were female. Majority of patient were between the age of
18-40 years, mean age being 33.4 years. In 31 cases there was previous history of drug intake. Commonly
affected sites include genitals and lips, palms and soles followed by extremities and other sites.
Most common causative drug was due to antimicrobial followed by NSAIDs.
Conclusion: Although clinical presentation of most of the patient was similar a detailed history, physical
examination and drug provocation test helped us to reach most of the diagnosis.

Keywords: Fixed drug eruption, Provocative tests.

Doi : 10.18231/j.ijced.2019.069

How to cite : Sahu V K, Gupta B, A clinico-aetiological study of fixed drug eruption amongst the patient attending tertiary care centre. IP Indian J Clin Exp Dermatol 2019;5(4):332-335

Copyright © 2019 by author(s) and IP Indian J Clin Exp Dermatol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)