COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804


Print ISSN:-2581-4710

Online ISSN:-2581-4729

CODEN : IIJCBS

Current Issue

Year 2020

Volume: 6 , Issue: 1

Article Access statistics

Viewed: 516

Emailed: 0

PDF Downloaded: 190

IP Indian Journal of Clinical and Experimental Dermatology


Clinico-Metabolic profile of Xanthelasma palpebrum


Full Text PDF Share on Facebook Share on Twitter


Author Details : Savita Chaudhary, Samreen Haque

Volume : 4, Issue : 1, Year : 2018

Article Page : 22-25


Suggest article by email

Abstract

Introduction: Xanthelasma palpebrum (XP) is a disorder of lipid metabolism that usually presents as bilateral and symmetrical, soft velvety papules and plaques around the eyelids. Though various factors contribute to its etiology, a strong association with lipid metabolism is proposed. Usually seen in middle age people, its main concern is cosmetic appearance.
Objective: 1. To evaluate the lipid profile, glycemic levels, Body Mass Index (BMI) in patients with Xanthelasma palpebrum. 2. To find the association between parameters like age, sex and comorbid illness with Xanthelasma palpebrum.
Materials and Methods: This prospective study included 42 clinically diagnosed patients with Xanthelasma Palpebrarum and 95 subjects in control group with non-inflammatory skin disorders. Levels of serum triglyceride, cholesterol, HDL, LDL, VLDL, blood sugar - fasting and post prandial were determined in all cases along with body mass index and blood pressure. These parameters were compared in both groups and association with XP was analysed.
Results and Discussion: In our study, XP was more common in females compared to males. In our study of patients with XP, average fasting blood sugar was 108 gm% and average post prandial blood sugar was 152gm%. Average serum triglyceride levels in patients with XP was 171.4 mg/dl, compared to 108.4 mg/dl in control group with significant p value i.e. 0.001, suggesting strong correlation between XP and serum triglyceride levels.
Conclusion:  Patients with XP usually visit doctor with cosmetic concern. In most of the cases of XP, serum cholesterol, triglyceride and VLDL levels are deranged. Patients with XP should be evaluated for above parameters and systemic management done along with treatment of XP.

Keywords:  Xanthelasma  Palpebrum (XP), Low Density Lipoprotein (LDL), High Density Lipoprotein (HDL), Very Low Density Lipoprotein (VLDL),  Body Mass Index(BMI), Diabetes Mellitus (DM).

Doi : 10.18231/.2018.0005

How to cite : Chaudhary S, Haque S, Clinico-Metabolic profile of Xanthelasma palpebrum. IP Indian J Clin Exp Dermatol 2018;4(1):22-25

Copyright © 2018 by author(s) and IP Indian J Clin Exp Dermatol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)