COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804

Article view: 210

Article download: 94

IP Indian Journal of Clinical and Experimental Dermatology


A case-control study evaluating association of serum vitamin D level with alopecia areata


Full Text PDF Share on Facebook Share on Twitter


Author Details : Sudhanshu Sharma, Abhishek Singh*, Sanjeet Panesar, Bhawna Chaudhary

Volume : 5, Issue : 3, Year : 2019

Article Page : 186-190


Suggest article by email

Abstract

Introduction: Evidance has suggested that Vitamin D may play a vital role in the pathogenesis of alopecia
areata (AA). Vitamin D may prove as a geme changer in the management of alopecia patients.
Aim: To study find the correlation, if any, between Alopecia areata and levels of Vitamin D.
Materials and Methods: This investigation included 100 cases of alopecia areata with age- and sexmatched
healthy persons. Study subjects were grouped as per extent, pattern and severity of alopecia.
Levels of vitamin D were evaluated and group wise comparision was made between cases and controls.
Correlations were derived after analyzing the collected data.
Results: Mean serum Vitamin D levels was found to be 22.8710.03 ng/ml among cases. Serum Vitamin D
level was found to be 26.0410.06 ng/mL where scalp involvement was between 0%–24%. Levels droped
to 24.63 9.82 ng/mL when scalp involvement was 25%–49%. Levels of Vitamin D further dropped to
11.914.18 ng/mL and 11.914.18 ng/mL where scalp involvement was graded as S4 and S5 respectively.
Negative correlation (r = ???? 0.264) was noted between extent of Alopecia Areata and Vitamin D levels.
Serum Vitamin D level was found to be 25.589.82 ng/mL among subjects graded as having alopecia
circumscripta. Levels of Vitamin D further dropped to 12.28 5.06 ng/mL and 11.27 5.90 ng/mL where
extent of scalp involvement was graded as alopecia totalis and alopecia universalis respectively.
Conclusion: Vitamin D levels were unsatisfactory in the study subjects of group 1(cases) in relation to
subjects of group 2(controls). Vitamin D levels had inverse correlation with the pattern of alopecia in
these patients. Such findings points towards a probable association between alopecia areata and Vitamin D
deficient levels.

Keywords: Casecontrol study, Alopecia areata, SALT score, Vitamin D.

Doi : 10.18231/j.ijced.2019.040

How to cite : Sharma S, Singh A, Panesar S, Chaudhary B, A case-control study evaluating association of serum vitamin D level with alopecia areata. IP Indian J Clin Exp Dermatol 2019;5(3):186-190

Copyright © 2019 by author(s) and IP Indian J Clin Exp Dermatol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)