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IP Indian Journal of Clinical and Experimental Dermatology

Cutaneous changes in pregnancy: A comprehensive study of 700 cases at a tertiary care centre from South India

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Research Article

Author Details : H Bangaru*, R Sudha, Nanjundaswamy Bisalvadi Lingaiah, S Sathish, KAK Surendran

Volume : 5, Issue : 3, Year : 2019

Article Page : 249-254

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Introduction: Pregnancy is associated with many skin changes, due to profound immunologic, metabolic,
endocrine and vascular changes occur during pregnancy. Though most of which are physiological in nature,
there can be changes in pre-existing skin diseases or develop new pregnancy specific dermatoses which can
cause distress to pregnant female and may influence the fetal outcome as well.
Aims: To study the frequency and pattern of skin changes in pregnant women.
Study Design: Prospective cross sectional study in a tertiary care centre
Materials and Methods: After obtaining institutional ethical committee approval, a prospective
cross-sectional study carried out in the outpatient department of obstetrics and gynaecology and Skin,
Cheluvamba and KR Hospital, Mysuru. A total of 700 pregnant females were screened for physiological
skin changes, associated dermatological diseases and specific dermatoses of pregnancy.
Statistical analysis used: M S word
Results: A total of 700 pregnant women were included in the study, of which 309(44.1%) were
primigravida and 391(55.9%) were multigravida. Physiological skin changes were seen in all cases, out
of which Linea nigra was the most common change seen in 610(87.14%) cases, specific dermatoses
of pregnancy (PSD) were seen in 58(8.28%) cases, out of which Atopic eczema of pregnancy (AEP)
was the most common, seen in 36(62.06%) cases followed by pruritic urticarial papules and plaques of
pregnancy (PUPPP), observed in 18(31.03%)cases and Intrahepatic cholestasis of pregnancy (ICP) was
seen in 4(6.89%) cases and among other concomitant dermatological disorders fungal infection was the
most common seen in 72 cases (10.28%).
Conclusions: Many skin changes occur during pregnancy are physiological require no treatment.
Pregnancy specific dermatoses are not very rare, few PSDs have impact on pregnancy and fetal outcome,
likely to recur in subsequent pregnancy, require thorough examination and specific diagnosis to counsel
and manage accordingly.

Keywords: Atopic eczema of pregnancy and PUPPP, Pregnancy dermatoses.

Doi : 10.18231/j.ijced.2019.053

How to cite : Bangaru H, Sudha R, Lingaiah N B, Sathish S, Surendran K , Cutaneous changes in pregnancy: A comprehensive study of 700 cases at a tertiary care centre from South India. IP Indian J Clin Exp Dermatol 2019;5(3):249-254

Copyright © 2019 by author(s) and IP Indian J Clin Exp Dermatol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (