COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details.,, Mob. 8826373757, 8826859373, 9910947804

Article view: 175

Article download: 103

Indian Journal of Clinical and Experimental Ophthalmology

Role of 2% rebamipide ophthalmic suspension in the management of dry eye disease

Full Text PDF Share on Facebook Share on Twitter

Research Article

Author Details : D N Prakash, Sujata Sajjan*, K Satish, Raghavendra R, Mohammed Abdul Kayoom

Volume : 5, Issue : 4, Year : 2019

Article Page : 461-465

Suggest article by email


Objective: To study the therapeutic effects of 2% rebamipide ophthalmic suspension in dry eye disease.
Materials and Methods: It was Prospective study of 80 patients diagnosed with dry eye syndrome from
Jun 2016 to April 2017. After complete ophthalmic examination all were treated with 2% rebamipide
suspension. Dry eye-related Symptom Score, anterior segment examination with slit lamp, Tear Film
Break-Up Time, Fluorescein Ocular Surface Staining Score(FOS) & Schirmer test were used to collect
data from patients at baseline & at 2, 4, 8 & 12 week visits.
Results: Mean dry eye-related symptom score showed a significant improvement from baseline at 2, 4,
8 & 12 weeks (9.80, 7.20, 7.40 & 7.83 points). Median FOS also showed significant improvement from
baseline (3.0 points) at 2, 4, 8 & 12 weeks (2.0, 2.0, 1.0 & 1.0 points respectively). TBUT & Schirmer test
values also improved but were not significant after treatment.
Conclusion: 2% rebamipide ophthalmic suspension is an effective in treating dry eye. It helps in improving
both ocular & tear film stability.

Keywords: Dry eye syndrome, Tear film, Rebamipide, Mucin Secretion.

Doi : 10.18231/j.ijceo.2019.110

How to cite : Prakash D N, Sajjan S, Satish K, Raghavendra R, Kayoom M A, Role of 2% rebamipide ophthalmic suspension in the management of dry eye disease. Indian J Clin Exp Ophthalmol 2019;5(4):461-465

Copyright © 2019 by author(s) and Indian J Clin Exp Ophthalmol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (