COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details.,, Mob. 8826373757, 8826859373, 9910947804

Article view: 165

Article download: 86

Indian Journal of Clinical and Experimental Ophthalmology

Study on progression of primary open angle glaucoma in patients with maintained target intraocular pressure

Full Text PDF Share on Facebook Share on Twitter

Research Article

Author Details : Snehal Sardas Shende*, Kavita Kumar, Priti Singh, Rohan Jain

Volume : 5, Issue : 4, Year : 2019

Article Page : 565-569

Suggest article by email


Purpose: To study progression of primary open angle glaucoma in patients with maintained target
intraocular pressure.
Materials and Methods: This was a prospective observational study comprising 30 diagnosed patients
of primary open angle glaucoma on maintained target intraocular pressure conducted for a period of 2
year. Patients underwent complete ophthalmic examination including IOP, optic disc evaluation & visual
fields. Systolic and diastolic blood pressure was measured with sphygmomanometer using adult cuff size.
Systolic, diastolic & mean ocular perfusion pressure ocular perfusion pressure were calculated. Patients
were examined at baseline then at 12 months then at next 12 months. Progression of glaucoma was accessed
on the basis of changes in VF ’ s &optic disc between baseline and final follow at 2 years. Data analyzed
using standard statistical technique and a probability value ( ‘ p ’ value) of < 0> statistically significant.
Results: Mean age of study participates was 540.07 years ,M:F ratio was 1.5:1.Progressive patients
showed significantly changes in optic disc cupping C:D ratio f0.670.11gat baseline tof0.740.13gfinal
follow up (p<0> up(p<0> progressive group. DBP, DOPP and MOPP were significantly lower in progressive group as compared
to non-progressive group.
Conclusions: Low DBP, low MOPP, and low DPP are risk factor for primary OAG progression with
maintained target intraocular pressure, providing further evidence of a vascular mechanism in glaucoma

Keywords: Primary Open Angle Glaucoma (POAG), Visuals Fields (VF), Mean Deviation (MD), Patterned standard deviation(PSD), Cup: Disc ratio (C:D), Systolic blood pressure(SBP), Diastolic blood pressure(DBP), Systolic Ocular Perfusion Pressure(SOPP), Diastolic Ocular Perfusion Pressure(DOPP), Mean Ocular Perfusion Pressure(MOPP).

Doi : 10.18231/j.ijceo.2019.129

How to cite : Shende S S, Kumar K, Singh P, Jain R, Study on progression of primary open angle glaucoma in patients with maintained target intraocular pressure. Indian J Clin Exp Ophthalmol 2019;5(4):565-569

Copyright © 2019 by author(s) and Indian J Clin Exp Ophthalmol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (