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Volume: 6 , Issue: 1

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Indian Journal of Clinical and Experimental Ophthalmology

A rare case report of orbital malignant solitary fibrous tumor

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Case Report

Author Details : Priyam Gupta, Gupta N, Chinmayee Thrishulamurthy*, Dayananda S Biligi

Volume : 5, Issue : 4, Year : 2019

Article Page : 593-596

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Purpose: Orbital Solitary Fibrous Tumor (SFT) is a rare spindle cell neoplasm of mesenchymal origin.1
We describe the clinical presentation, radiological features, pathological features of a 23yr old female
patient with orbital malignant SFT.
Observation: We report a case of Malignant Orbital Solitary Fibrous Tumor of the orbit in a 23yr old
female who presented with painless unilateral proptosis of the left globe noticed by her in the last 1
month. Computed Tomography scan showed a well-defined homogeneous enhancing soft tissue density
in superior and extraconal compartment, with no evidence of bony erosion or calcification. Enbloc tumor
resection confirmed SFT based on histopathological and immunohistochemistry studies. Microscopic
examination showed a highly cellular tumor, moderate amount of pleomorphism and increased mitosis
(>4/10). Immunohistochemistry studies confirmed diagnosis as tumor was diffuse positivity with CD34,
BcL2 positive, STAT6 positive with ki 67 high i.e. a 9-10% proliferative index in hot spot areas. Desmin,
CD99, S100 and EMA was negative. Patient subsequently was also given External Beam Radiotherapy.
Conclusion: Solitary Fibrous Tumors are rare tumor, which should be included in differential diagnosis of
soft tissue tumor of the orbit. Combination of Computed Tomography scan, histological examination and
immunohistochemical markers provide an accurate diagnosis. Complete surgical resection along with long
term follow up is essential.

Keywords: Solitary fibrous tumor (SFT), Proptosis, Tumor.

Doi : 10.18231/j.ijceo.2019.135

How to cite : Gupta P , Gupta N, Thrishulamurthy C, Biligi D S, A rare case report of orbital malignant solitary fibrous tumor. Indian J Clin Exp Ophthalmol 2019;5(4):593-596

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