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Indian Journal of Clinical and Experimental Ophthalmology


A retrospective study: impact of various phases of menstrual cycle on corneal pachymetry


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Research Article

Author Details : Aneesha Kardam Vyas*, Poonam Rana, R N Kothari, Zeel Patel, Avani Soni

Volume : 6, Issue : 1, Year : 2020

Article Page : 114-116


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Abstract

Aim: To evaluate the effect of the various phases of menstrual cycle on corneal pachymetry.
Materials and Methods: 100 female participants were selected retrospectively, who underwent a through
screening and ophthalmic evaluation. Corneal pachymetry was measured using an ultrasound pachymeter.
Readings of both the eyes were taken on day 1-3, day 13-15 and day 26-28 of the menstrual cycle. An
intergroup comparison was carried out and statistical significance was found.
Results: It was found that the corneal thickness was at its thickest i.e. 547.51 31.824 on day 13-15 which
coincides with ovulation and thinnest i.e. 548.25 29.948on day 1-3 of the menstrual cycle (p<0> Conclusion: All in all, we conclude that hormonal changes do affect the ocular structures in a profound
manner. In view of the cornea, they have a role in disturbing the pump mechanism of corneal endothelium,
especially when oestrogen levels are at their highest. This eventually leads to a physiological increase in
corneal thickness due to corneal edema and having an indirect effect on visual acuity and corneal sensitivity
and intraocular measurement.

Keywords: Cornea, Pachymetry, Oestrogen, Menstrual cycle.

Doi : 10.18231/j.ijceo.2020.025

How to cite : Vyas A K, Rana P, Kothari R N, Patel Z , Soni A, A retrospective study: impact of various phases of menstrual cycle on corneal pachymetry. Indian J Clin Exp Ophthalmol 2020;6(1):114-116

Copyright © 2020 by author(s) and Indian J Clin Exp Ophthalmol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)