COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804

Article view: 22

Article download: 20

Indian Journal of Clinical and Experimental Ophthalmology


Role of intravitreal dexamethasone implant in HIV associated macular edema: A retrospective clinical trial


Full Text PDF Share on Facebook Share on Twitter


Research Article

Author Details : Kaushik Sadhukhan, Bivas Bala*

Volume : 6, Issue : 1, Year : 2020

Article Page : 129-132


Suggest article by email


Abstract

Aim: To investigate the role of intravitreal sustained release dexamethasone implant in AIDS associated
macular edema.
Materials and Methods: This hospital based retrospective interventional study (nonrandomized) was
conducted in Malda Medical College, West Bengal, India from September2017 to august 2019 where
18 eyes of 18 patients with HIV were included. After proper history taking and required investigations,
intravitreal sustained release dexamethasone implant was injected to each patient in respective eye under
topical anaesthesia with strict aseptic measures and utmost care. Institutional clearance and written
informed consent from each patient were taken before the procedure. Best corrected visual acuity (BCVA)
and intraocular pressure (IOP) measurement and central macular thickness (CMT) evaluation by spectral
domain optical coherence tomography (SD-OCT) were performed at baseline and after 1 month, 3 months,
6 months of injection. The data obtained then were put for paired t test using SPSS software.
Results: All patients had shown improvement in terms of BCVA as well as reduction of central macular
thickness (CMT). 12 patients had increased IOP at first visit for which topical anti glaucoma drugs were
prescribed and on subsequent visits their IOP were under control.
Conclusion: Intravitreal sustained release dexamethasone implant is a good option to tackle macular edema
in HIV infected patients.

Keywords: Acquired immune deficiency syndrome, Best corrected visual acuity, Central macular thickness, Human immunodeficiency virus, Immune recovery uveitis, Intraocular pressure, Macular edema, Spectral domain optical coherence tomography.

Doi : 10.18231/j.ijceo.2020.028

How to cite : Sadhukhan K, Bala B, Role of intravitreal dexamethasone implant in HIV associated macular edema: A retrospective clinical trial. Indian J Clin Exp Ophthalmol 2020;6(1):129-132

Copyright © 2020 by author(s) and Indian J Clin Exp Ophthalmol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)