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Year 2019

Volume: 5 , Issue: 4

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Indian Journal of Clinical and Experimental Ophthalmology


Evaluation of dry eye disease in patients with diabetic retinopathy


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Research Article

Author Details : Rimsha Thaseen*, Rahul Sahay, Shilpa Goyal, Anuj Khullar, Dharmendra Singh

Volume : 5, Issue : 2, Year : 2019

Article Page : 193-197


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Abstract

Introduction: Due to lack of correlation between symptoms and signs in dry eye disease, changes in tear film parameters and ocular surface health have shown wide variance across different studies worldwide. The present study evaluated the efficacy Schirmer, tear film break-up time (TBUT) and conjunctival impression cytology (CIC) in type 2 diabetics with retinopathy.
Materials and Methods: The scoring of Schirmer test, TBUT, and CIC was compared in 75 eyes of diabetics with retinopathy and 75 eyes of age and sex matched healthy controls. The diagnostic accuracy of these test for dry eye diagnosis was estimated using receiver operating curve (ROC) analysis.
Results: Dry eye indices showed a significant reduction (P<0 P=0.645), P=0.478), P=0.676) P=0.345) AUC=0.982)>TBUT (AUC=0.948) >Schirmer (AUC= 0.864), respectively.
Conclusion: Tear film characteristics and ocular surface health in patients with type 2 diabetes mellitus with retinopathy include decreased tear production as well as tear film stability with worse Nelson grade (squamous metaplasia), respectively. Second, the accuracy of CIC to evaluate dry eye in patients with diabetes was higher as compared to TBUT and Schirmer. All diabetic patients should be examined for tear film and ocular surface changes irrespective of the stage of retinopathy.

Keywords: Conjunctival impression cytology, Dry eye, Receiver operating curve, Schirmer Test, Tear film break-up time, Type 2 retinopathy.

Doi : 10.18231/j.ijceo.2019.046

How to cite : Thaseen R, Sahay R , Goyal S, Khullar A, Singh D, Evaluation of dry eye disease in patients with diabetic retinopathy. Indian J Clin Exp Ophthalmol 2019;5(2):193-197

Copyright © 2019 by author(s) and Indian J Clin Exp Ophthalmol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)