COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details.,, Mob. 8826373757, 8826859373, 9910947804

Article view: 209

Article download: 89

Indian Journal of Clinical and Experimental Ophthalmology

Patterns and predictors of isolated oculomotor nerve palsy recovery following mild traumatic brain injury

Full Text PDF Share on Facebook Share on Twitter

Research Article

Author Details : Sudha Menon, Girish Menon*, Lakshmiprasad G, Neetha I R K

Volume : 5, Issue : 3, Year : 2019

Article Page : 343-347

Suggest article by email


Introduction: Oculomotor nerve palsy following mild traumatic brain injury is uncommon. The exact pathogenesis, management protocol and outcome of such patients is unclear in the absence of large series. This article attempts to analyze the patterns of injury and recovery in a series of twenty one patients with third cranial nerve palsy following mild traumatic brain injury (TBI).
Materials and Methods: All patients admitted with mild head injury and third nerve involvement were included in the study. This retrospective study covered a three-year period from January 2015 to December 2017. Mild head injury was defined as patients with a Glasgow Coma score of 14 -15 and having a normal CT scan at admission. The clinical profile of the injury and recovery of the oculomotor nerve were jointly evaluated and followed up in the department of neurosurgery and ophthalmology.
Results: Our study group included twenty one patients. Levator palpebrae superioris involvement with ptosis (95.23%) was the most consistently affected third nerve function followed by extraocular muscles (90.47%) and pupillary fibers (80.9%). Ptosis was partial in 11 patients and complete in nine. Of the extra ocular muscles, the most common muscles to be involved were the inferior rectus and the medial rectus which were involved in 19 patients (90.47%). Superior rectus involvement was seen in 13 patients and inferior oblique in nine patients. Imaging including thin section CT scans (all patients) and FIESTA MRI sequence (2 patients) did not reveal any significant abnormality. All our patients were managed conservatively. Steroids and corrective surgery was not tried in any patient. On follow up, after a mean period of 6 months, partial ptosis recovered completely while complete ptosis recovered only in four patients (44.4%).  Of the seventeen patients with pupillary involvement, pupillary size and reaction improved in four (23.5%) and remained static in 13 patients. Of the extraocular muscles superior rectus (9/13) and inferior oblique (6/9) appeared to have a better recovery than inferior rectus (09/19) and medial rectus (08/19).
Conclusion: Isolated oculomotor nerve palsy following minor head injury is uncommon. The exact pathogenesis is unclear. Advanced MRI sequences may reveal structural lesions along the course of the third cranial nerve in few cases. Pupillary fibers are most susceptible to injury and have the least rate of recovery. Partial ptosis recovers well. Recovery of extraocular muscle paresis is inconsistent. Management is essentially symptomatic and the outcome is unpredictable.

Keywords: Oculomotor nerve palsy, Traumatic head injury.

Doi : 10.18231/j.ijceo.2019.082

How to cite : Menon S , Menon G, Lakshmiprasad G, Neetha I R K, Patterns and predictors of isolated oculomotor nerve palsy recovery following mild traumatic brain injury. Indian J Clin Exp Ophthalmol 2019;5(3):343-347

Copyright © 2019 by author(s) and Indian J Clin Exp Ophthalmol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (