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IP Indian Journal of Immunology and Respiratory Medicine

Clinicopathological profile of primary lung cancer in a tertiary care teaching hospital in the south-east coast of India

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Research Article

Author Details : Chilamakuru Raghavendra, G Ram Kumar Gupta*, V Venkata Ramana Reddy

Volume : 4, Issue : 4, Year : 2019

Article Page : 205-209

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Introduction: Lung is one of the commonest sites for neoplasms both primary and metastatic cancers.
Identification and determination of histopathological play a major role in the diagnosis and treatment of
cancer. Radiology and imaging helps in the selection of procedures to obtain a tissue sample for the
diagnosis and management of lung cancer. The present study was aimed to analyze the clinic-pathological
profile of primary lung cancer in the south-east coast of India.
Materials and Methods: A prospective, observational study was conducted in the Department of
Pulmonary Medicine, Maharaja Institute of Medical Sciences (MIMS), Vizianagaram, Andhra Pradesh,
India. A total of 104 patients with primary lung cancer were enrolled. Radiological, clinico pathological
profile and Histopathological analysis was done individually for all patients.
Results: Male patients (70.1%) were more compared to females (29.9%). The Average age of the study
population was 57.8 years. A total of 70(67.3%) study subjects had a history of smoking comprising of 61
males and 9 female subjects. Almost all study patients had clinical presentations of cough and shortness of
breath (100%). Most common X-ray and CT chest radiographic feature was mass lesion (n=89 and n=91).
Adenocarcinoma was identified in 79 patients (76.0%) as the most common histological type and it was
also common in both smokers (n=49) and nonsmokers (n=29).
Conclusions: The most common histological variant was Adenocarcinoma followed by squamous cell
carcinoma. Among men, smoking is the principal risk factor in the causation of lung cancer. A precise,
accurate and rapid screening method is still warranted for the diagnosis of primary lung cancer.

Keywords: Adenocarcinoma, Bronchoscopy, Clinico-pathological profile, Histopathological profile, Primary lung cancer.

Doi : 10.18231/j.ijirm.2019.047

How to cite : Raghavendra C, Gupta G R K, Reddy V V R, Clinicopathological profile of primary lung cancer in a tertiary care teaching hospital in the south-east coast of India. IP Indian J Immunol Respir Med 2019;4(4):205-209

Copyright © 2019 by author(s) and IP Indian J Immunol Respir Med. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (