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IP International Journal of Maxillofacial Imaging

Massive Osteolysis of the Mandible (GORHAMs Disease) - A Rare Case Report

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Author Details : S. Padmashree, Lekshmy J, Shilpa Sastry, Rema Jayalekshmy, Rachna Kaul

Volume : 1, Issue : 1, Year : 2015

Article Page : 20-25

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Massive Osteolysis (Gorhams Disease) is a rare, insidious, chronic disease characterized by progressive resorption of contiguous osseous structures. In 1838, Jackson first described a case of disappearing humerus. Condition is exceedingly rare with less than 150 cases have since been described in the international literature, with fewer than 35 involving a maxillofacial site, usually the mandible. The exact cause of this disease remains unknown, but ongoing clinical research attempts to better understand the etiology. Here we are presenting an unusual and rare case report of a 7 year old female pediatric patient diagnosed as massive osteolysis involving mandible. The purpose of this case report is to raise awareness of the condition and to highlight the clinical and radiological findings that would make the oral diagnostician consider it as a rare differential diagnosis in lesions of facial skeleton. To the best of our knowledge, our case report represents the fourth case in the literature to document Massive osteolysis in a female pediatric patient with mandibular involvement.

Keywords: Gorhams disease, Osteolysis, Mandible

How to cite : Padmashree S, Lekshmy J, Sastry S, Jayalekshmy R, Kaul R, Massive Osteolysis of the Mandible (GORHAMs Disease) - A Rare Case Report. IP Int J Maxillofac Imaging 2015;1(1):20-25

Copyright © 2015 by author(s) and IP Int J Maxillofac Imaging. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (