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IP International Journal of Medical Microbiology and Tropical Diseases


A prospective study of incidence of cervical HPV infection & its association with aetiological factors & cervical cancer in adult women of Jamnagar


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Research Article

Author Details : Rashmika Dhaval Parmar, Dhaval Jugabhai Parmar*

Volume : 5, Issue : 4, Year : 2019

Article Page : 193-197


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Abstract

Introduction: Etiological link between cervical cancer & HPV is independent of other risk factors but their
geographic variations need to be explored. Cervical cancer with profile of Sexually Transmitted Disease
has consistent causal connection with persistent cervical HPV infection, so such carrier women are at High
risk. Thus, study evaluate risk of HPV infection in women of Jamnagar region by exploring aetiological
determinants related to their sexual life.
Aim: To explore incidence of cervical HPV infection along with its association with cervical cancer as
well with commonly proposed aetiological factors in adult women of Jamnagar
Materials and Methods: The study was conducted in 2004 on random 110 women attending Gynecology
out patient department of GG Hospital at MPSGMC Jamnagar by taking their cervical smear and
administering them questionnaires about their sexual life. HPV infection was diagnosed based on
cytopathic effects of HPV, by Microbiological staining techniques. Association of cervical HPV positive
status of women in relation to common aetiological factors and carcinoma cervix were analyzed.
Results: 10.9% of women exhibited cervical HPV infection out of them 20% belonged to higher age group
(50-59 years) followed by 16.6% of young age group (20-29). 15.3% of women with HPV infection were
having 6 -10 years of active married life. Accordingly 18.18% HPV infected women were multipara -
bearing 3 - 4 children whereas nullipara had no HPV infection. 75% of women with carcinoma cervix were
positive for cervical HPV which endorse strong causal connections.
Conclusions: Study concludes that cervical HPV is prevalent in 10.9% adult women of Jamnagar region
and is significantly attributable to cervical cancer. HPV positive woman have profile of sexually active
life of initial years, early age at first coitus or had longer but active married life, so sexual transmission
happens to be the predominant mode of HPV acquisition. Similarly, multiparity has aetiological association
with positive cervical HPV. Study reflects women’s HPV status at single point in time, so longitudinal
observations are recommended. However, certain recommendations are made considering associated
aetiological factors as guiding principle to derive HPV prevention strategy.

Keywords: Cervical HPV, Cevical cancer, STD.

Doi : 10.18231/j.ijmmtd.2019.044

How to cite : Parmar R D, Parmar D J, A prospective study of incidence of cervical HPV infection & its association with aetiological factors & cervical cancer in adult women of Jamnagar. IP Int J Med Microbiol Trop Dis 2019;5(4):193-197

Copyright © 2019 by author(s) and IP Int J Med Microbiol Trop Dis. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)