COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804

Article Access statistics

Viewed: 708

Emailed: 0

PDF Downloaded: 167

IP International Journal of Medical Microbiology and Tropical Diseases


Adhesins of Uropathogenic Escherichia Coli (UPEC)


Full Text PDF Share on Facebook Share on Twitter


Author Details : Sabitha Baby, Vimal Kumar Karnaker, Geetha R K

Volume : 2, Issue : 1, Year : 2016

Article Page : 10-18


Suggest article by email

Abstract

Uropathogenic Escherichia coli (UPEC) is the main pathogen associated with urinary tract infections namely cystitis, pyleonephritis and infectious complications. As a commensal, E.coli is mostly harmless in the gut. Some strains diverge and become more pathogenic. They express multiple virulence factors and invade the urinary tract (UT). The important ones are the ‘adhesins’ or specialized proteins with sticky ends, which help to break the inertia of urinary bladder mucosa and help to attach to them.
Host immune response trigger inflammatory reactions, resulting in symptoms of urinary tract infections (UTI). Recent studies help to get updated information about the molecular mechanisms behind the adhesins. This knowledge is helpful for better understanding of the pathogenesis of UTI which can then be applied to epidemiological research. It also helps to understand the revolutionary trends, to help with better prognosis and to devise new methods in lab diagnosis & vaccine development. This review is intended to unravel the molecular components that makeup the adhesions of UPEC.

Key words:
Adhesins, AFA, Curli, CUP, Pap, SFA, UPEC

 

How to cite : Baby S, Karnaker V K, Geetha R K, Adhesins of Uropathogenic Escherichia Coli (UPEC). IP Int J Med Microbiol Trop Dis 2016;2(1):10-18

Copyright © 2016 by author(s) and IP Int J Med Microbiol Trop Dis. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)