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IP International Journal of Medical Paediatrics and Oncology


Efficacy of oral zinc as an adjuvant therapy in acute diarrhea in children aged 5-15 years


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Research Article

Author Details : Anil Bapurao Kurane, Saiprasad Onkareshwar Kavthekar*, Varun Ramchandra Bilagi, Poonam Kiran Hittangi

Volume : 5, Issue : 1, Year : 2019

Article Page : 1-5


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Abstract

Introduction: Zinc as an adjuvant therapy in acute diarrhea has been proved effective in children aged below 5 years. Presently there are no any guidelines for the use of zinc in children above 5 years  of age. So we studied efficacy of zinc as an adjunct therapy in acute diarrhea in children aged 5-15 years.
Materials and Methods: This hospital based longitudinal comparative study was conducted in D.Y.Patil medical college and hospital, Kolhapur, Maharashtra. 200 children aged 5-15 years, admitted with acute diarrhea with dehydration were included.100 children received zinc (study group), orally 20 mg once a day for 14 days & another 100 were not received zinc (control group). Primary and secondary outcome measures in terms of frequency of loose stools per day at 24, 48 hours and on 7th day of admission and duration of hospital stay respectively were compared. The data was analyzed statistically.
Results: 75% & 25% children from study group and 27% & 69% from control group had frequency of loose stool ? 5 times and 6-7 times per day at 48 hours respectively. 3% and 78% children from study and 0% and 46% from control group had frequency of loose stool < 2>th day respectively. In study group 88% children were discharged by 4th day and 76% from control group were discharged by 6th day with 2 days lesser hospital stay in children of study group. (P <0>
Conclusion: Oral zinc as an adjuvant therapy was effective in acute diarrhea in children aged 5 -15 years.

Keywords: Acute diarrhea, Children, Zinc.

 

Doi : 10.18231/j.ijmpo.2019.001

How to cite : Kurane A B, Kavthekar S O, Bilagi V R, Hittangi P K, Efficacy of oral zinc as an adjuvant therapy in acute diarrhea in children aged 5-15 years. IP Int J Med Paediatr Oncol 2019;5(1):1-5

Copyright © 2019 by author(s) and IP Int J Med Paediatr Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)