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Indian Journal of Microbiology Research

A study on steroids and immunosuppressants as risk factors for infections in SLE patients

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Research Article

Author Details : V Shiney John*, N Rathnapriya, S Vasanthi

Volume : 6, Issue : 4, Year : 2019

Article Page : 317-322

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Introduction: Systemic lupus Erythematosus (SLE) patients are inherently at risk for infections. Steroids
and other immunosuppressants used for treating SLE patients further increase the chances of infections.
This study was done to find the association of immunosuppressants with the risk of development of
infections in patients with SLE.
Materials and Methods: Appropriate samples were collected from 110 SLE patients with various
infections and processed in Microbiology laboratory. Treatment history was also collected from the patients
and analysis was done on infections in these patients.
Results: Daily prednisolone dosage 20 mg was associated with increased risk of infection with p value
of < 0> p value <0> Conclusion: Since there is strong association between higher dose of steroids and Cyclophosphamide
therapy with risk of infections in SLE patients, judicious use of these drugs is recommended.

Doi : 10.18231/j.ijmr.2019.068

How to cite : John V S, Rathnapriya N, Vasanthi S, A study on steroids and immunosuppressants as risk factors for infections in SLE patients. Indian J Microbiol Res 2019;6(4):317-322

Copyright © 2019 by author(s) and Indian J Microbiol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (