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Indian Journal of Microbiology Research

A study of aerobic bacterial profile and their antibiogram in patients with chronic osteomyelitis with special references to staphylococcus aureus

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Research Article

Author Details : B Neeharika*, R Vinod, Gerard Rakesh

Volume : 6, Issue : 4, Year : 2019

Article Page : 350-354

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Introduction: Chronic osteomyelitis is a important medical illness among developing countries, it is a very
expensive disease for the patient and society mostly associated with trauma and surgery as risk factors.
There is a constant change in the trend of organisms involved and resistance pattern seen with advent of
newer antibiotics, So early and specific therapy is needed. With this background present study aims to look
for the varying trends of microorganisms involved in osteomyelitis and their antimicrobial susceptibility
Materials and Methods: A total of 100 cases studied over a period of one year, samples processed by
following standard laboratory protocols and along with routine antimicrobial testing screening for MRSA
Results: Among 100 cases, 76 were males and 24 were females, between age group of 11 –60
years. Long bones are most involved with trauma (45%) as risk factor. Staphylococcus aureus (51%)
predominant pathogen isolated with 27(53%) were MRSA, followed by Pseudomonas aeruginosa (16%).
Antibiotic sensitivity testing of gram positive organisms showed hundred percent sensitivity to Linezolid
and Vancomycin with poor sensitivity to Pencillin (10/15.6%). Among gram negative organisms,
majority showed highest sensitivity to Amikacin (73.3%) & Imipenem (71.1%) with poor sensitivity to
Ciprofloxacin (20.0%) and Ampicillin (0%).
Conclusion: Chronic osteomyelitis is a prime challenging problem in many countries with severe
morbidity. Mostly due to neglect, delayed or inadequate treatment and emerging drug resistant pathogens
involved. Culture based antibiotic therapy helps in effectively treating the disease also prevents the drug

Keywords: Chronic osteomyelitis, MRSA, Staphylococcus aureus.

Doi : 10.18231/j.ijmr.2019.074

How to cite : Neeharika B , Vinod R, Rakesh G, A study of aerobic bacterial profile and their antibiogram in patients with chronic osteomyelitis with special references to staphylococcus aureus. Indian J Microbiol Res 2019;6(4):350-354

Copyright © 2019 by author(s) and Indian J Microbiol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (