COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details.,, Mob. 8826373757, 8826859373, 9910947804

Print ISSN:-2394-546X

Online ISSN:-2394-5478


Current Issue

Year 2020

Volume: 7 , Issue: 1

Article Access statistics

Viewed: 630

Emailed: 0

PDF Downloaded: 231

Indian Journal of Microbiology Research

Study of biofilm production and its correlation with antifungal resistance among Candida species isolated from suspected cases of Tuberculosis

Full Text PDF Share on Facebook Share on Twitter

Author Details : Anusuya Devi D., Sharadadevi Mannur Y.

Volume : 4, Issue : 1, Year : 2017

Article Page : 48-51

Suggest article by email


Background: Production of the biofilm may be considered as a virulence factor because it shows resistance towards many antimicrobial agents. Candida albicans is the most commonly isolated fungal pathogen and cause severe secondary infections in immuno-compromised population, including tuberculosis patients. This study was aimed to speciate Candida isolates, production of biofilm and its antifungal susceptibility pattern.
Materials and Methods: Totally 178 sputum specimens were screened by RNTCP Unit were included in the study. The clinical isolates of candida were identified by using conventional methods and their ability to produce biofilm formation was detected by the tube method. Antifungal susceptibility testing was carried out by direct susceptibility method using CHROM agar.
Results and Conclusion: Out of 178 sputum samples, Candida albicans 26 (72.2%) was the predominant species isolated. Strong biofilm production was seen with Candida albicans (47.2%), Candida parapsilosis (8.3%) and C.kruseii (5.5%) whereas C.dubliniensis (2.7%) was found to be weak biofilm producer. The biofilm positivity was found more with C.albicans (47.2%) as compared to Non-albicans Candida (18.1%).Antifungal resistance by Candida strains for Itraconazole, Nystatin, and Amphotericin B about 33.3%, 19.4% and 8.3% respectively.

Sabouraud’s Dextrose Agar (SDA), Non-Albicans Candida (NAC),Antifungal Resistance, Medical Devices

How to cite : Anusuya Devi D., Sharadadevi Mannur Y., Study of biofilm production and its correlation with antifungal resistance among Candida species isolated from suspected cases of Tuberculosis. Indian J Microbiol Res 2017;4(1):48-51

Copyright © 2017 by author(s) and Indian J Microbiol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (