COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804


Print ISSN:-2394-546X

Online ISSN:-2394-5478

CODEN : IJMR06

Current Issue

Year 2020

Volume: 7 , Issue: 1

Article Access statistics

Viewed: 731

Emailed: 0

PDF Downloaded: 246

Indian Journal of Microbiology Research


Patterns of antimicrobial resistance among Multi-Drug resistant Escherichia coli in a tertiary care centre in South Karnataka


Full Text PDF Share on Facebook Share on Twitter


Author Details : Soumya Kaup, Sunitha B. U., Jaya Sankarankutty

Volume : 4, Issue : 1, Year : 2017

Article Page : 52-58


Suggest article by email


Abstract

Introduction: Emergence of multi-drug resistant (MDR) organisms is an important public health concern especially in developing countries. The present study was carried out to assess the current antimicrobial pattern of multi-drug resistant Escherichia coli.
Materials and Methods: 346 consecutive, non-duplicate isolates of E. coli isolated during a period of two years were included in the study. The numbers of multi-drug resistant isolates were determined. Their antimicrobial resistance phenotypes and Multiple Antibiotic Resistance (MAR) index were determined.
Results: Among the 346 isolates of E. coli, 297 (85.84%) were multi-drug resistant with 61.3% of the isolates being resistant to drugs in more than five antimicrobial categories. The Multiple Antibiotic Resistance index of 82.7% of isolates was found to be greater than 0.2. Carbapenems, aminoglycosides, Chloramphenicol and Nitrofurantoin were found to be the most effective agents against MDR E.coli.
Conclusion: Antimicrobial resistance profiles of bacteria are ever-changing and periodic evaluation of resistance phenotypes of isolates is essential for the formulation of appropriate antibiotic policy and initiation of pertinent empirical therapy.

Keywords:
Antibiogram, Escherichia coli, Multi-drug Resistance, Multiple Antibiotic Resistance Index, Antibiotic Resistance Phenotypes

 

How to cite : Kaup S, Sunitha B. U., Sankarankutty J, Patterns of antimicrobial resistance among Multi-Drug resistant Escherichia coli in a tertiary care centre in South Karnataka. Indian J Microbiol Res 2017;4(1):52-58

Copyright © 2017 by author(s) and Indian J Microbiol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)